With new uses of Botox Cosmetic being explored every day (like a cure for depression, a temporary fix for a gummy smile and the unfortunately named Scrotox), it’s hard to believe the drug isn’t already approved by the U.S. Food and Drug Administration for all of its many indications. Even though the substance has been around since the ’50s and ’60s, it was only in 2002 that Botox Cosmetic received approval for treating frown lines and facial wrinkles (and it was just approved for use on crow’s-feet in 2013). Now, the FDA has approved the brand for use to treat forehead lines as well, making it the only neuromodulator on the market approved for use in wrinkles in three areas of the face—forehead lines, crow’s-feet and glabellar lines.

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